Chemical Genetics Screening Core

The CGSC is a Core resource for high throughput screening, available to the entire Washington University Community.
Functioning as a user facility, CGSC provides access to instrumentation, chemical libraries and expertise in automation and assistance in assay development for chemical genetics and drug discovery screening.

The CGSC is continuously looking for both users and projects looking to make use of chemical screening.

Libraries Available:

Spectrum Collection: ~2,000 cpnd.

ICCB Known Bioactives: ~500 cpnd.

Maybridge Hit-finder: ~15,000 cpnd.

ChemBridge Micro-Formats:~120,000 cpnd.

NCI Structural Diversity: ~2,000 cpnd.

Screening At CGSC:

The priceing of a screen can be most accurately determined by looking at our full priceing schedule and the examples linked to from that page

For a rapid estimate, a simple cost of $1.50/compound may be used

Many factors will affect pricing, contact us for an estimate on your project.

Our Instruments are also available for non screening operations, Contact us for more information.

Detection at the CGSC:

Multimode Plate reader:

Detection Modes:

- Fluorescence 200-900 nm

- Absorbance 200-999nm

- Luminescence

High Content Imager:

Objectives:

4x,10x,20x,40x, and 60x Super Fluor.

4x PhL,10x Ph1, 20x Ph1, and 40x Ph2

Filters:

FITC,TRITC DAPI, Texas Red

For More Information Contact the CGSC

Bill Nolan

Campus Box 8231

4566 Scott Ave, Rm. 366

St. Louis, Mo 63110

Office: 314.362.4445

Fax: 314.362.7183

Email: bnolan@biochem.wustl.edu

High Throughput Robotics

Chemical Genetics Screening Core

Lab Phone: 314.362.4478

http://htc.wustl.edu