The NCI Diversity set is a small library, ideal for beginning a screening campaign. It consists of a collection of 2,000 synthetic small molecules selected from the full NCI screening collection to allow users to focus their cancer screening efforts on a small scale.
Once users have validated their assay using a small collection like the Diversity set or the Known Bio-actives, they may focus screening efforts on the larger collections available at the CGSC, or through Moleculare Libraries/NCI.
The CGSC currently has copy 1400 of the Diversity Set in both 96 and 384-well format. Our stock is at 100 µm concentration, which will typically give 1 µm assay concentration.
Information on the compounds included in the set and the plate format can be retrieved from the NIH at http://dtp.nci.nih.gov/dtpstandard/ChemData/index.jsp (Search for plate numbers 1400-1424 to show the compounds in our current set.)